Faecal calprotectin concentrations in gastrointestinal diseases

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Faecal calprotectin in term and preterm neonates.

OBJECTIVES The aim of this review was to examine the characteristics of the faecal calprotectin assay in neonates and the evidence for its use as a noninvasive marker of intestinal illnesses during the neonatal period. METHODS Bibliographic searches were performed in the MEDLINE electronic database up to February 2010 looking for the following words (all fields): "infants" or "neonates" and "...

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Effect of age, gestation and lactation on faecal IgA and calprotectin concentrations in dogs*

Faecal calprotectin and IgA have been suggested as non-invasive markers of gut health. Faecal calprotectin is a marker of intestinal inflammation in adults, whereas IgA has been suggested as a marker of intestinal immunity. The purpose of the present study was to evaluate the effect of gestation, lactation and age on faecal concentrations of these biomarkers. Thirty puppies, nineteen pregnant o...

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Measurement of faecal calprotectin and lactoferrin in inflammatory bowel disease

Crohn's disease and ulcerative colitis are chronic relapsing gastrointestinal conditions characterised by an influx of inflammatory cells to the affected gut mucosa. The mainstay of diagnosing and re-evaluating these conditions in clinical practice and research is by invasive serological, radiological, endoscopic and histological assessment. In clinical trials, disease activity is often evaluat...

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Proton pump inhibitors may cause elevation in faecal calprotectin levels.

NICE has endorsed the use of faecal calprotectin (FCP) testing to enable clinicians to decide which of their patients presenting with diarrhoea may have inflammatory bowel disease or irritable bowel syndrome with diarrhoea (IBS-D). A normal result should reassure the clinician that their patient probably has IBS-D and this should obviate the need for a colonoscopy. I work in a community-based g...

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Elevated levels of faecal calprotectin in primary Sjögren’s syndrome is common and associated with concomitant organic gastrointestinal disease

BACKGROUND Primary Sjögren's syndrome (pSS) is a systemic rheumatic disease in which gastrointestinal (GI) symptoms are common. Faecal calprotectin (FC) is a non-invasive biomarker that has been suggested to discriminate organic intestinal disease from functional disorders. The purpose of this study was to explore the usefulness of FC testing in patients with pSS. METHODS In total, 56 consecu...

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ژورنال

عنوان ژورنال: Journal of International Medical Research

سال: 2013

ISSN: 0300-0605,1473-2300

DOI: 10.1177/0300060513488499